Ver Contraindicaciones. Elevaciones de ALT con el régimen VHC ombitasvir / paritaprevir / ritonavir, con o sin dasabuvir; suspender Nuvaring antes de iniciar el régimen VHC y reiniciar 2 semanas después de finalizar. No use con métodos de barrera femenina( por ejemplo, diafragma, capuchón cervical, condón femenino); el dispositivo de anillo puede interferir con su colocación y posición., Antagonized by hepatic enzyme inducing drugs (eg, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, St. John’s wort); use non-hormonal method or a backup contraception. May be potentiated by atorvastatin, acetaminophen, ascorbic acid, vaginal miconazole, or strong/moderate CYP3A4 inhibitors (eg, itraconazole, ketoconazole, voriconazole, fluconazole, grapefruit juice). May be affected by HIV/HCV protease inhibitors or NNRTIs., May antagonize acetaminophen, temazepam, salicylic acid, morphine, clofibric acid, lamotrigine. May potentiate cyclosporine, prednisolone, theophylline, tizanidine, voriconazole. May need dose adjustment of thyroid hormones. May affect lab tests (eg, coagulation factors, lipids, glucose tolerance, binding proteins, hormone binding globulins).