Se Kontraindikasjoner. ALT høyder med HCV-behandlingen ombitasvir/paritaprevir/ritonavir, med eller uten dasabuvir; slutte Nuvaring før du starter HCV-behandlingen og starte 2wks etter ferdigstillelse. Ikke bruk med kvinnelige barriere metoder (f.eks, membran, cervical cap, kvinnelig kondom); ring enheten kan forstyrre deres plassering og posisjon., Antagonized by hepatic enzyme inducing drugs (eg, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, St. John’s wort); use non-hormonal method or a backup contraception. May be potentiated by atorvastatin, acetaminophen, ascorbic acid, vaginal miconazole, or strong/moderate CYP3A4 inhibitors (eg, itraconazole, ketoconazole, voriconazole, fluconazole, grapefruit juice). May be affected by HIV/HCV protease inhibitors or NNRTIs., May antagonize acetaminophen, temazepam, salicylic acid, morphine, clofibric acid, lamotrigine. May potentiate cyclosporine, prednisolone, theophylline, tizanidine, voriconazole. May need dose adjustment of thyroid hormones. May affect lab tests (eg, coagulation factors, lipids, glucose tolerance, binding proteins, hormone binding globulins).